Anastrozole in Oligospermia Hyper Androgenic Subfertile Men
by Danish S. MAGICINE PHARMA | SEARCH LATEST MEDSAnastrozole 1 mg tablet is an
aromatase inhibitor used to treat oligospermia or the low production of sperm
in hyper androgenic sub fertile men. This condition, also known as male factor
infertility, refers to the decreased quantity or quality of male reproductive
cells in the semen and affects around 10-15% of couples worldwide. Anastrozole Tablet is an effective alternative to traditional treatments such as
glucocorticoids and gonadotropin therapy, as it has been found to improve semen
parameters and increase stem cell production.
Anastrozole effective action
Anastrozole dose works by inhibiting
the enzyme aromatase, which is responsible for the conversion of androgens
(male hormones) to estrogens (female hormones). It is often used as an adjuvant
treatment in combination with other anti-androgens, such as ketoconazole and
spironolactone, to reduce male sex hormones and improve fertility. By
inhibiting aromatase, Anastrozole also reduces the synthesis of estrogens in
the testes, resulting in increased testicular size and improved sperm count.
Results from clinical trials
In clinical trials, Anastrozole
tablets have been shown to significantly reduce androgen levels in the majority
of male patients with oligospermia. A study conducted in 2010 found that men
who took Anastrozole for four months experienced an increase in mean sperm
concentration from 6 million/mL to 34 million/mL. Another study similarly found
an increase in sperm motility, with a mean rise of 13.2%.
Treatment measures and side effects
Further, Anastrozole 1mg Tablet has been found to improve overall fertility rates in hyper androgenic sub fertile men, although exact figures and further studies are needed to confirm this. Anastrozole is also generally considered to have fewer side effects than treatments such as glucocorticoids and gonadotropin therapy. The most common side effects associated with it are nausea, hot flashes and headaches, although these do not usually last long and can generally be reversed if the patient stops taking the drug.
Conclusion
In conclusion, Anastrozole is an
effective treatment option for oligospermia in hyper androgenic sub fertile
men, with benefits such as increased sperm count, motility and improved overall
fertility rates. It is generally well-tolerated, with few side effects, making
it an attractive alternative to traditional treatments. However, further
research is needed to confirm the full extent of its impact on fertility, as
well as its long-term safety.
Source URL:- Anastrozole in Oligospermia Hyper Androgenic Subfertile Men
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Created on Jan 20th 2023 01:12. Viewed 143 times.