Articles

A comprehensive look at the ibrutinib cost & description

by MEDIXO CENTRE Pharmaceuticals
Description

The new anti-cancer drug ibrutinib (Imbruvica), developed by the J & J pharmaceutical company is significantly more effective than standard chemotherapy for leukemia. 
During the trial, some patients with chronic lymphocytic leukemia received ibrutinib, and some patients received chemotherapy. It turned out that in the first group the survival rates were 90%, in the chemotherapy group - 81%. The researchers note that in the group of participants receiving ibrutinib, remission rates were in four out of ten patients, in the chemotherapy group - four out of a hundred. When we talk about Ibrutinib price in USA then it comes to most expensive cancer medicine.
It should also be noted that patients responded more quickly to ibrutinib than to chemotherapy. Another advantage of the new drug over chemotherapy is the fewer side effects associated with its use.
Scientists believe that ibrutinib can replace standard chemotherapy. It is especially indicated for patients who have developed resistance to chemotherapy.  

Indications for use

Ibrutinib should be taken once a day with a glass of water at approximately the same time every day. Ibrutinib capsules must be swallowed whole with water; Do not open, break or chew capsules. Imbruvica should not be taken with grapefruit juice.

Treatment of adult patients with chronic lymphocytic leukemia who have received at least one line of therapy, or patients with a 17p deletion or TP53 mutation who have contraindications to chemo immune therapy, as first-line therapy.
Ibrutinib is prescribed in specific doses that are modified depending on the type of cancer being treated. When administered orally, it is taken every day and the amount is adjusted depending on the patient's condition and responsiveness to treatment.

• Chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL): 420 mg once daily is the standard dose for these conditions. Everything applies both to the treatment of patients and to people who were previously treated.
• Mantle cell lymphoma (MCL): 560 mg daily is recommended for patients with MCL. This is usually the case in patients who have received at least one prior therapy.
• Waldenström Macroglobulinemia (WM): In the treatment of WM, it is recommended to take 420 mg once a day.
• Marginal zone lymphoma (MZL): 420 mg daily is prescribed to patients with MZL who require systemic therapy and have received at least one prior anti-CD 20-based treatment.

Patients should strictly follow the recommended doses. Ibrutinib should be taken at the same time every day to keep the blood as uniform as possible. It can be taken with or without food, but patients should not consume grapefruit products or Seville oranges as they affect the effectiveness of this medication. It should be monitored periodically by a healthcare professional who can adjust the dosage if necessary and monitor side effects. Patients are not allowed to modify or stop the medication without consulting their doctor, as this modification may affect the effectiveness and safety of the treatment.

Side Effects/Caution

Ibrutinib is a powerful drug used to treat cancer. However, it can have different side effects. Patients should be aware of these possible reactions and use caution:

Common side effects:
• Diarrhoea
• Fatigue
• Muscle and bone pain
• Nausea
• Rash
• Fever
• Constipation
• Difficulty breathing
• bruises

Precautions 

• Caution should be used when using Ibrutinib in patients with a history of heart disease, infection, or bleeding disorders.
• Routine blood tests are needed to track counts of different types of blood cells and indications of complications.
• The patient should tell the healthcare provider about all other medications being used, since Ibrutinib can affect many medications.
• Stay away from grapefruits and Seville oranges during treatment, as they may interfere with Ibrutinib in the blood.

Generic Ibrutinib in India

Ibrutinib in India costs significantly less than brand-name Imbruvica, allowing patients to better manage their finances if they need this essential cancer treatment. The provision of generic versions in India is part of a broader effort undertaken by the country to make critical medicines available, particularly for life-threatening diseases such as cancer. These generics are produced according to high standards and regulations, meaning they can be considered reliable options for patients. Generic Ibrutinib in India is considerably cheaper than its available in United states & other countries. Some Indian brands are available such as Ibrunat, Bdbrut, Nitib etc. These low prices are mainly due to the pricing policies of pharmaceutical products in India and high competition among local manufacturing companies.



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About MEDIXO CENTRE Freshman   Pharmaceuticals

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Joined APSense since, December 23rd, 2023, From New delhi, India.

Created on Apr 17th 2024 03:36. Viewed 67 times.

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