Why Are Immunosuppressive Drugs Used During Pregnancy?
Immunomodulatory drugs (IMDs) are used to treat autoimmune disorders, such as rheumatoid arthritis, lupus, multiple sclerosis, and psoriasis. These drugs are also sometimes prescribed for other medical conditions, such as asthma, Crohn’s disease, ulcerative colitis, and inflammatory bowel disease.
What Is an Immunomodulator?
An immunomodulator is a medication that helps regulate the immune system by suppressing inflammation or stimulating the body’s own defenses against infection. IMDs work by either blocking the production of antibodies or preventing them from binding to cells. They can also help reduce the activity of T cells, B cells, macrophages, neutrophils, natural killer cells, dendritic cells, mast cells, basophils, eosinophils, and platelets.
When Should You Take Them?
There are several different types of immunomodulatory drugs (IMDs) available for use during pregnancy. These medications are usually taken after conception and continue throughout pregnancy. However, some women choose to take an IMD before becoming pregnant. This type of treatment is called preconceptional therapy.
Which Drugs Are Used During Pregnancy?
The Food and Drug Administration (FDA) has approved three classes of IMDs for use during pregnancy: corticosteroids, azathioprine(Imuran), and cyclosporine. Corticosteroids are often prescribed to reduce inflammation associated with asthma, allergies, and other conditions. Azathioprine (Imuran)is used to treat inflammatory bowel disease and rheumatoid arthritis. Cyclosporine is used to treat organ transplant rejection. All three of these medications carry risks, so it’s important for patients to discuss them with their healthcare providers.
Who Can Benefit from Taking Them?
Patients who take immunomodulatory drugs during pregnancy should talk to their doctors before taking any medication. They should also monitor their blood pressure, weight gain, and fetal growth closely.
Common Side Effects
Immunomodulatory agents are used to treating autoimmune disorders such as rheumatoid arthritis, lupus, and psoriasis. These drugs work by suppressing the immune system so that it does not attack healthy tissue. However, some patients develop side effects while taking them.
Originally published on https://richard104.medium.com/why-are-immune-modulators-used-during-pregnancy-6f1d05dd2f91
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