Hydroxypropyl Methyl Cellulose

by Kritika Agarwal Satisfy our customers

Hydroxypropyl methyl cellulose (HPMC) from HPMC Manufacturers China is a hydrophilic colloid derived from cellulose with hydroxypropoxyl and methoxy groups. It is used in ophthalmic preparations such as viscosifiers, in wetting dispersions for contact lenses and in artificial tears. It has been found that a dispersion of HPMC at 2% 4000 cps with these characteristics does not produce inflammation, is tolerated by the human eye and is able to cover the intraocular content. Hydroxypropyl methyl cellulose is white non-ionic cellulose ether in the form of powder, has no smell or taste.

Applications of Hydroxypropyl methylcellulose: Hydroxypropyl methyl cellulose is used in the pharmaceutical industry as a granule binder and as a coating agent. It is also used as a stabilizing agent of suspensions and emulsions.

It is used to avoid coalescence (it is the process in which two phase domains of essentially identical composition come into contact to form a larger phase domain) and the formation of sediments since it acts as a protector of colloids. Other uses include its use in the manufacture of capsules, adhesive in plastic bandages, moisturizing agent in ophthalmic drops and artificial tears, it is also used in the production of cosmetics and food products.

Hydroxypropyl methylcellulose from HPMC Supplier China is used in industries such as petrochemical, construction, ceramics, spinning, synthetic resin, coating, electronic and food. In the construction industry it is used as a water retention agent and cement mortar retarder.

Maintenance of adequate levels of cholesterol: The soluble fiber HPMC from HPMC Factory China, especially in high viscosity grades, can significantly decrease plasma total and LDL cholesterol levels. In addition, this fiber has the advantage of not being fermented by the intestinal flora, so it does not produce the typical effects of this type of fermentation.

The mechanism by which HPMC has hypocholesterolemic effect is not completely established, an explanation is that by forming viscous gels it is difficult to contact the intestinal wall and the luminal content. In the same way as other soluble fibers, hydroxypropyl methyl cellulose could reduce or decrease the absorption of cholesterol, bile acids and carbohydrates.

Decrease in the postprandial glycemic response.

The postprandial glycemia is the elevation of blood glucose concentrations after eating, this response is variable depending on the nature of the food consumed and can be of different measure and duration.

Hydroxypropyl methylcellulose causes a decrease in the postprandial glycemic response, because it generates viscous solutions in the gastrointestinal tract. The reason why the dietary fibbers produce this effect seems to be the delay of the gastric emptying, the reduction of the access of the digestive enzymes to their substrates and the reduced diffusion to the absorption surface of the intestine.

This retarding effect is very beneficial for diabetics. Although in healthy people, who have a normal tolerance to glucose has not yet been shown that this decrease has physiological effects, it seems that it could be beneficial as it helps to decrease the response to insulin and the expression of hepatic lipogenesis and therefore both would favour the prevention of some diseases such as type 2 diabetes or fatty liver.