CD31 antibody & VEGF antibody
by Biorbyt Ltd Tools for ScienceBiotechnology is the utilisation of biological processes for manufacturing scientific
reagents and for other scientific purposes. Essentially, biological reagents
are components that are used in bio-chemical analysis to evaluate biological
processes. They can be used to generate antibodies that are used to target
specific protein targets, which are known as antigens. Immunohistochemistry is the process of
detecting antigens in cells of a tissue section and Western blot first
separates a protein mixture via SDS-PAGE and then using the primary antibody to
detect the protein of interest. This works by exploiting the binding of
antibodies to specific epitopes on the protein that are in biological tissues.
CD31
antibody: Cluster of Differentiation
31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1)
is a type I integral membrane glycoprotein; and an element of the
immunoglobulin super-family of cell surface receptors. CD31 is constitutively
expressed on the exterior of endothelial cells where it is concentrated at cell
junctions. CD31 antibody
is also expressed at low levels on all leukocytes and platelets. Homotypic
interaction of CD31 is important in cell-cell interaction, cell-matrix
interaction and signal transduction. The CD31 antibody is primarily used on a rabbit or
mouse, but is also frequently used on human cells where the antibody binds to CD31. Consequently, this can help
to evaluate the degree of tumour angiogenesis,
which can entail a hastily growing tumour. Additionally, it can be used as
markers for myeloid progenitor cells and distinguish various subsets of myeloid
leukemia infiltrates (granular sarcomas).
VEGF antibody: Vascular Endothelial Growth Factor is a signal protein that is formed by
cells that stimulates vasculogenesis and angiogenesis. It is part of
the system that restores the oxygen supply to tissues when the blood
circulation is insufficient. Serum concentration of VEGF is high in bronchial asthma and low in diabetes
mellitus. VEGF's standard utility is to produce new
blood vessels during embryonic
development, new blood vessels after injury, muscle
following exercise, and new vessels (collateral circulation) to bypass blocked vessels. VEGF antibodies are
commonly used in research applications such as Flow Cytometry,
Immunocytochemistry/Immunofluorescence, Immunohistochemistry,
Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin,
Immunoprecipitation, and Western Blot. VEGF can be used in a variety of model
species i.e. Bovine (cow), Canine (dog), Porcine (pig), Mouse, Rat, Sheep, and tested
on Human tissues. Biorbyt offers a great selection on several antibody products;
and the VEGF antibody can drastically help scientists facilitate their
research further.
You can safely purchase the CD31 antibody & VEGF antibody
to test
in various laboratories from Biorbyt Ltd. They are a trusted online antibody
and protein supplier that offers great quality products to be sent prompt and
securely to your address.
Sponsor Ads
Created on Dec 31st 1969 18:00. Viewed 0 times.