Articles

CXCL13 antibody & VEGFR2 antibody

by Biorbyt Ltd Tools for Science

There are many scientists around the world in the biotech industry that are dedicated to finding cures for a variety of diseases. Biotechnology is the utilisation of biological processes for manufacturing scientific reagents and for other scientific purposes. These scientists undergo rigorous scientific training and often have many years of experience in bench work. The vital research focuses on an assortment of different types of cancer and heart diseases. Cancer research has advanced considerably during the last decade, and a multitude of qualified reagents and antibodies are now at the scientists’ disposal to continue to assess the focal causes. The scientific community is an international network with major research efforts taking place globally; and 35% of all scientific publications are from the USA.

CXCL13 antibody: The chemokine CXCL13, also known as BCA-1 or BLC, belongs to the CXC chemokine family. CXCL13 is formed by cells in the omentum and from peritoneal macrophages, and in adoptive transfers. CXCL13 and its receptor CXCR5, manage the organisation of B cells inside follicles of lymphoid tissues. It is renowned to dictate homing and motility of B cells in lymphoid tissue and develops the ectopic lymphoid tissue in chronic inflammation. In T-lymphocytes, the CXCL13 expression is able to replicate a germinal centre origin of the T-cell. In addition, CXCL13 antibody can provide great assistance to test the diagnosis of Angioimmunoblastic T-cell lymphoma. Moreover, the neutralisation of CXCL13 inhibits the development of collagen-induced arthritis (CIA) and decreases follicular reaction in lymphoid and nonlymphoid tissues. Therefore, the results can have significant implications concerning the pathogenesis and treatment of autoimmune arthritis. These antibodies can be tested on a wide range of applications, such as WB, IHC-P, and P-ELISA. As a result, the CXCL13 antibody can be tested on various instruments such as a rabbit or on a human placenta tissue.

VEGFR2 antibody: VEGFR-2 (Vascular endothelial growth factor receptor 2) is a tyrosine-protein kinase and receptor for VEGF or VEGFC. VEGFR is a transferable angiogenic growth factor that is a key stimulant of the growth and maintenance of a vascular network in embryogenesis and the vascularization of unyielding tumors. It can be useful for scientists in HIV-1 disease cases. The VEGFR-2 interaction with extracellular viral Tat protein enhances angiogenesis in Kaposi's sarcoma lesions. The common tested applications to use are WB, IHC-P, and P-ELISA. Furthermore, the VEGFR2 antibody can be tested on a Mouse, Rat, Pig, Rabbit, Cow, Chicken, Dog, and a Human. Consequently, VEGFR-2 blockade is more efficient in inhibiting angiogenesis and tumor growth.

Biorbyt Ltd is a trustworthy antibody and proteins supplier that offers a wide range of antibodies, proteins, reagents and small molecules. They can be used by bench scientists for academic research, biological research, pharmaceutical research, disease research and many more. The CXCL13 antibody and VEGFR2 antibody can easily be ordered online, with a quick and secure delivery.


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Created on Dec 31st 1969 18:00. Viewed 0 times.

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