by Ada Brown PhD
An Flt-3/Flk-2 inhibitor; In vitro: IC50 = 1.1 nM and 4.2 nM (for FLT3-ITD and wt FLT3, respectively)
Recommended Features
  • High purity
  • High effectiveness
  • cost effective
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Review on Quizartinib

Quizartinib is an orally available small molecule with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell proliferation and apoptosis.

Good quality with reasonable price.-Marry Golden

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About Ada Brown Freshman   PhD

1 connections, 2 recommendations, 38 honor points.
Joined APSense since, May 25th, 2015, From New York, United States.

Created on Nov 9th 2016 03:12. Viewed 512 times.


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