Quizartinibby Ada Brown PhD
An Flt-3/Flk-2 inhibitor; In vitro: IC50 = 1.1 nM and 4.2 nM (for FLT3-ITD and wt FLT3, respectively) Recommended Features
- High purity
- High effectiveness
- cost effective
Review on QuizartinibQuizartinib is an orally available small molecule with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell proliferation and apoptosis.
Good quality with reasonable price.-Marry Golden
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Created on Nov 9th 2016 03:12. Viewed 278 times.
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