Stem Cell Treatment for Parkinson’s Disease

by VAISHNAV KUMAR Online Marketing Expert

Parkinson’s disease is one of the major neurological disorders, making many people helpless in India. Recently, scientists have started getting links on the onset of the disease occur.

Parkinson’s is a kind of progressive neurological disorders, caused by the gradual loss of dopamine producing cells. Our brain is the central organ involved in controlling measure activities of our body. Neurons are the cells, carrying all information from brain to respected organ, to complete the action. An immediate question arises in our mind, that how these neurons work in such a great coordination. Each neuron has long projections that are attached to another neuron forming a network of cells. These neurons secrete a type of neurotransmitter, which is basically the chemical, transmitted to other neurons in the form of messenger.

Motor control, motivation, lactation, arousal, cognition and reward are some of the functions performed by Dopamine. Neruons, whose primary neurotransmitter is dopamine are very few in number in comparison to other neurons. These neurons are mostly confined to the central region of the brain known as “ Substantia Nigra”. The progressive loss of these dopaminergic neurons in the substantia Niagara region is the major cause of motor function deficits in Parkinson’s patients. However, for many years scientists were working hard to find out what is the possible cause of the degeneration of the neurons in the particular region. Extensive studies on mouse models, revealed the fact that, these dopaminergic neurons in the substantia nigra region of the brain are very sensitive as compared to their other counterparts in different region. When there is the strong accumulation of certain toxic proteins known as “Synovial Proteins flakes”, these neurons will react with the immediate sparking of electrical impulses. As a result of high stress and oxidative response of electrical impulses, these neurons die to degenerate.

Currently, there is no cure for Parkinson’s disease, except for some drugs or intravenous dopamine injections, which can slightly ease symptoms associated with the disorder, but no one can either reverse the pathophysiology or even slow down the progression of disorder. Stem cell treatment has the solution for Parkinson’s. Recent development in stem cell conversion into neurons or dopamine producing cells, have justified, the assumptions that stem cell treatment can be effective in treating patients with Parkinson’s diseases.

Stem cells are the mother cells of the body, which are able to give rise to many new cells if directed in the proper channel. These stem cells, thus can even give rise to neurons, or dopamine producing cells, which are the prerequisites to treat Parkinson’s disorder. These stem cells can be isolated from bone marrow or adipose tissue, which are known to be the richest sources of stem cells and can be put back into the targeted area of the body, after minimum manipulation in the laboratory. Autologous stem cell treatments are thus a very safe, efficient method, posing no risk to the patient.

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