ROLE OF ‘HUMIDITY NEUTRAL’-OXYGEN SCAVENGERS IN PROTECTING PHARMACEUTICALS
by Oxygen Absorber Manufacture Oxygen Absorber | INDIA For any Pharmaceutical company, maintaining the desired standard quality of the pharmaceuticals from the storage to till the distribution is a challenging task. Therefore, special measures which are appropriate to avoid contamination from chemical or microbial nature which flourishes in presence of moisture and oxygen need to be observed and practiced which affect during quality control. One such measure which is practiced by Pharmaceutical companies which turned out to be effective during packaging is the interjection of humidity-neutral oxygen scavengers in the containers. These Oxygen scavengers absorb oxygen from the moisture present in the surrounding environment in a package thereby inhibiting microbial reproduction, which causes degradation of active ingredient of the medicine. Oxygen scavengers act as a means in reducing the oxygen content as well as the moisture content inside the pharmaceutical packaging and ensure the physical stability of the drugs. Not only microbial, chemical factors such as extreme levels of pH can also be controlled using these Oxygen Scavengers. Pharmaceutical Decomposition due to hydrolysis is also restricted by deploying Oxygen Absorbers.Oxygen scavengers or Oxygen absorber are
made or synthesized from chemicals which are non-toxic and non-editable
available in the form of Oxygen
Absorber Packets or Oxygen Absorber Sachets.
What
is in Oxygen Absorber Sachets?
Oxygen Absorber Sachets are porous sachets
which contain ferrous iron powder along with activated carbon and salt having a
tendency of attracting or suspending the water molecules in between them based
on the hygroscopic phenomenon and thereby absorbs the total oxygen content present
in the surrounding atmosphere in a package.
How
to use Oxygen Absorber packets?
Since pharmaceutical products remain in a closed package for longer periods, the moisture
levels inside the package increase with a slight increase in relative humidity
and temperature in the surroundings. Therefore, Oxygen absorber which is available in packets or sachets is placed in the packages containing
pharmaceutical drugs do increase the rate of absorption of oxygen and prevent
the ingress of oxygen. Transportation of commodities like Pharmaceutical
products in bulk quantities is performed through depending mainly on sea logistics. There are many other modes of
transportation, but sea logistics serve to be cost-effective
unless the Containers are subjected to Container rain. Therefore these Oxygen
Absorbers Sachets Place inside the containers or even inside the packages serve
to be a better absorbent or dehumidifier in withstanding the extreme climatic
conditions prevailing around the containers during transportation. Therefore,
before shipment placing the Oxygen Absorber Sachets are placed at the bottom or
side walls of the containers help in
maintaining the thermal variations throughout the period of transportation and thereby contributing for the
safe passage of Pharmaceutical commodities.
Ageless
Oxygen Absorbers:
Since the Oxygen Absorber packets play a major role in extending the
shelf life of packages they are named as Ageless by the patents as they protect
the Pharmaceutical Packaging materials with low RH environments and preserve
them for a longer period. They are trade named as ageless Oxygen Absorbers and
are available in Sachets forms with specifications such as “oxygen absorption
capacity-C” and headspace of the
containers. These specifications make their deployment easy for preservations
for a limited period of time.
100ccOxygen
Absorbers: It is used for Vacuum Sealed
Pharmaceutical packaging containing one package for long time preservations
such as Vitamins.
300ccOxygen
Absorbers: It is used for Vacuum Sealed
Pharmaceutical packaging containing more than one package for long time
preservations.
500ccOxygen
Absorbers: It is used for Vacuum Sealed
Pharmaceutical packaging containing bulk quantity for long time preservations.
All these 100ccOxygen Absorbers, 300ccOxygen
Absorbers, 500ccOxygen Absorbers are specially designed to store emergency
pharmaceutical products for longer periods. These are available in Mylar bags
which are specially designed by BoPet (Biaxially-oriented polyethylene terephthalate) plastic which is sandwiched
between two thick aluminum Foils. The features
such as-transparency, chemical-stability, insulating capacity makes it viable
and is used for commercial applications such as Oxygen Absorbers packing which
in turn are used for storing packed products with chemical origin. It also
meets the pharmacopeia, regulatory limits. This Oxygen absorber sachet reduces
the access of heat, protects the medicinal products from light, act as
water-proof and regulates the oxygen transmission levels.
The growth rate usage Of Oxygen Absorbers in Healthcare and
Pharmaceutical preservations globally is expected to grow, thereby increasing
the production Volume. Therefore, Oxygen Absorber manufacturers in India, which
supply Industrial Units pertaining to Healthcare
preservations and Pharmaceutical preservations on a large scale as well as on a
small scale, based on quality assurance and performance criteria are also
flourishing well. Since, Oxygen Absorbers can be used for a wide variety of
storage of drugs which include-Anti depressants, anti-anxiety drugs, Cannabis, Dissociative
Drugs, Hallucinogens, Narcotics, Stimulants and many more, employing the best
suppliers of oxygen absorbers, who are rendering their services in delivering the Absorbents according to the
specifications and Dimensions meeting both Small scale as well as Large-scale requirements are of utmost
importance.
The Global competitive standards of
humidity-neutral oxygen scavengers to meet the Pharmaceutical applications are
growing day by day because of their excellent absorption capacity of oxygen at
varying RH. As the relative humidity increases the adsorption capacity of the
absorbers also increases. Therefore, quality standards of oxygen absorbers
cannot be compromised, since they last for longer periods along with the
packages until the delivery. Before placing the order for oxygen absorber
packets these guidelines are helpful in safe storage of Pharmaceuticals causing
no harm to public health and the environment.
The aspects to be considered are -
Ø The Size of the Pharmaceutical products
Ø The Specifications of the product
Ø The Quality of the product
The choice of deploying Oxygen absorber
packets ensures protection from the storage until
the delivery and usage.
Since Pharmaceutical products are mainly drugs that are chemically
synthesized to cure the immunological diseases,
they are also very expensive and need to be properly packaged to ensure the
efficiency of the drug. Hence, these Oxygen scavengers are playing a crucial
role in protecting the quality of the Pharmaceutical products and ensuring the
safe delivery after manufacturing to till the usage.
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Created on Dec 10th 2018 03:08. Viewed 447 times.