peptide mapping analysis
It is important to make sure the protein therapeutics, such as recombinant proteins, peptides and monoclonal antibodies, are biosynthesized correctly. Peptide mapping works as a powerful analytical approach to confirm the identity of a specific protein, detail characterization of the protein& screen and identify PTMs. The purified proteins/peptides are reduced into short peptides by protease cleavage or chemical cleavage, then separated and analyzed with MALDI-TOF and ESI-TOF o identify the peptide sequence by peptide mass fingerprints. A cocktail of proteases usually are used to generate more unique peptides.
Our technical team of scientists pioneered the optimal methods used for peptide and protein sequencing. When peptide mapping alone is not enough, Creative Proteomics can utilize a range of techniques, LC-MS, LC-MS/MS, Nanospray to ensure your protein is sequenced to the extent possible.
Creative Proteomics is the proteomics division of Creative Dynamics Inc, an integrated CRO company that provides a full range of drug development services, including Molecular Biology, Biochemistry, Systems Biology, Organic Chemistry, Genomics, Bioinformatics, Structural Biology, Preclinical and Clinical studies.
contact us: contact@creative-proteomics.com
Tel: 6316269181
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