Magnesium Carbonate Pharmaceutical Grade Use For Stomach MgCO₃by Hu Yanchao Magnesium oxide manufacturers in China
Magnesium carbonate tablets are a common digestive drug and can be used for a variety of stomach problems. Many people know that it can neutralize stomach acid, but the effect of magnesium carbonate is not limited to this.
What profit does magnesium carbonate have to the stomach?
1. Neutralize stomach acid
Magnesium carbonate is an anti-acid. 1g of magnesium carbonate can neutralize 27.1 ~ 27.8mmol of hydrochloric acid. Human gastric juice is mainly composed of hydrochloric acid secreted by gastric gland cells. Gastric acid plays an extremely important role in the process of food digestion. If gastric acid is secreted too much, it will have an erosive effect on the gastric mucosa, causing inflammation or ulcers in the stomach. This is where antacids are needed to neutralize excess stomach acid.
2. Maintain the PH value of the stomach
Magnesium carbonate neutralizes stomach acid and keeps the stomach pH between 3 and 5, mainly due to the properties of magnesium carbonate. When the stomach pH is less than 3, magnesium carbonate begins to neutralize, preventing excessive gastric acid from eroding the gastric mucosa.
When pH=5, the reaction was terminated to avoid the aggravation of gastric acid secretion caused by the high pH value in the stomach. When the pH is less than 3, the reaction restarts, thus keeping the pH in the stomach in the proper range.
3. Adsorption and binding
Magnesium carbonate can directly inhibit its activity by adsorption and binding to gastric acid protease, which is conducive to the repair of ulcer surface. It can also bind bile acid and absorb hemolytic phosphorylcholine, thus preventing further damage and destruction of gastric mucosa caused by these substances.
4. Protect the gastric mucosa
Magnesium carbonate can stimulate the gastric mucosa to increase the synthesis of prostaglandin E2, and prostaglandin E2 can regulate the normal secretion of gastric acid, and also has a certain protective effect of gastric mucosa, so it can enhance the function of "gastric mucosal barrier". In addition, magnesium carbonate can also promote the release of epidermal growth factor in gastric mucosa, increase the content of phospholipid in the hydrophobic layer of mucous substratum, and prevent the damage of gastric mucosa caused by hydrogen ion reverse osmosis.
Therefore, magnesium carbonate is suitable for a series of diseases caused by excessive gastric acid: 1. Gastric ulcer, duodenal ulcer, acute and chronic gastritis and duodenal ambidextrous inflammation; 2. Reflux esophagitis;3. Symptomatic treatment of gastric discomfort related to excessive gastric acid, such as heartburn, acid reflux, abdominal distension, nausea, vomiting and other symptoms.
Mei Shen is the world's leading producer of magnesium oxide, Magnesium oxide is an oxide of magnesium, an ionic compound. It is a white solid at room temperature. Magnesium oxide exists in the form of periclase in nature and is a raw material for magnesium smelting. Magnesium oxide is white or light yellow powder, odorless, tasteless, this product is insoluble in water and ethanol, melting point 2852 ° C, boiling point 3600 ° C, magnesium oxide has high refractory insulation properties. It can be converted into crystal by burning at a temperature above 1000 ° C. If it rises above 1500 ° C, it will form a burnt magnesia or sintered magnesia.
Magnesium oxide can be used in the manufacture of metallurgy, smelting, advanced magnesia bricks, refractory materials and moisturizing materials. It is also widely used in rubber, rubber sheet, rubber products, pharmaceutical industry, food industry, plastic sheet accelerator, glass fiber reinforced plastics and Surface coating of silicon steel sheet, paper production, steel ball polishing, leather treatment, insulation materials, grease, dyes, ceramics, desiccant, resin, flame retardant, etc.
Hebei Mei Shen Chemical Technology Group is the main magnesium oxide producer in the world. It is also the largest magnesium salt producer in China and has won the ISO9002 quality system certification. It also has GMP-Certification.
With rich experience in the research, development, production, management and operation of magnesium oxide products, Mei Shen Group has always attached great importance to the research and development of new products and strict requirements on product quality. MeiShen has a high-level sales team. The business covers more than 20 countries and regions around the world. It is widely welcomed by new and old customers.
MeiShen has a high-level sales team. The business covers more than 20 countries and regions around the world. It is widely welcomed by new and old customers.
Created on May 25th 2020 01:13. Viewed 204 times.