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Lorazepam Vs.Diazepam, which works better for Anxiety?

by Xanax Online Over the counter sleeping pills uk

Lorazepam and diazepam are all-inclusive medications that help to treat anxiety disorders. Anxiety disorders are more common among mental health conditions.

Do both the medications fall under the category of benzodiazepines?
Yes, they do fall under the category of benzodiazepines.

Is the mechanism of both the medications the same?
Yes, both these work by enhancing the activity of GABA (gamma Amino Butyric acid in the brain).

What is the effect of gamma-aminobutyric acid in the brain?
GABA is an inhibitory chemical that can block certain nerve signals. In addition to it, it helps in boosting the mood and also can produce a calming effect.

Under what category. do these medications fall?
Both these medications fall under the schedule four category of drugs which is being described by the drug enforcement administration(DEA). It means that both these medications have the risk of abuse and dependence. Therefore, it is recommended to use it as a short-term therapy and that too under the supervision of a healthcare provider.

What is the main point of difference between diazepam and lorazepam?
The main difference is durability . that is for how long a drug can stay in the system? Diazepam tends to stay longer in the body than lorazepam. While lorazepam(Ativan)has a half-life of only 18 hours, on the other hand, diazepam has a half-life of about 48 hours. Therefore, depending upon the duration. Based on duration lorazepam is an intermediate-acting benzodiazepine. While On the other hand diazepam is a longer-acting benzodiazepine.

What is the basis of the metabolism of both these medications?
Lorazepam and diazepam have different metabolism. How does lorazepam is metabolized in the liver?
Lorazepam is metabolized in the liver by a process known as glucuronidation while on the other hand diazepam is metabolized in the liver only by the cytochrome enzymes. Diazepam has more potential to interact with other drugs as compared to lorazepam.

What are the strengths of these medications?
Lorazepam is available in the market in the form of oral tablets and there are different strengths such as 0.5 mg, 1 mg, and 2 mg. Ativan has different strengths such as 2 mg, 5 mg, and 10 mg.

How can you administer Ativan?
 It is advisable to administer Ativan in the form of oral solutions, solution for injections, and rectal gel.

Do both medications are used for treating anxiety disorders?
Yes. Both medications are used to treat anxiety disorders.

Do both the medications help to treat Insomnia caused by anxiety?
Yes, these do but diazepam is used as off-label.

Do both the medications help to deal with Alcohol withdrawal syndrome?
Ativan is an off-label on the other hand diazepam is used in regular mode.

Do these medications help to deal with Muscle spasms
Ativan UK is off-label while diazepam is used in the regular mode.

Do these medications help to deal with Seizure disorders?
Yes, both medications help to deal with seizure disorders.

Do these medications help to deal with Status epilepticus?

Yes, these help to deal with status epileptics.

Do these medications help to deal with Sedation or premedication before surgery? 

Yes, doctors advise it to use with sedation or premedication before surgery.

What is more effective lorazepam vs diazepam?
Both lorazepam and diazepam UK are effective for treating anxiety disorders. 

What are the criteria that will decide what is the more effective benzodiazepine?
It depends upon the condition which you are going to treat, other medications you are going to take, and any other treatment that have been previously decided.



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Created on Dec 16th 2021 13:46. Viewed 239 times.

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