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However, there were some points of difference between the effects of IGF-1 in the noise exposure and brain lesions of the cochlea. First, the threshold attenuation occurred one day after the injury of ischemia and reperfusion model. By contrast, there were only 14 days after exposure to noise. Second, save HC were different types between these two conditions: the loss of HC internal and external attenuated in models of stroke and noise exposure, respectively. These results suggest several points about the effect of IGF-1 in the hazardous and noxious substances. (1) IGF-1 has the ability to influence both in the early and late of Hazardous and Noxious Substances stage. (2) IGF-1 has the processing power to protect both internal and external damage HC. (3) IGF-1 has different effects on mammals, namely, rats, guinea pigs, gerbils and Mongolian.
HC numbers maintained by the treatment of IGF-1 mechanisms
Individuals are documented stress levels by using concentrations of Hair Vitality (eg cortisol) in the blood, saliva, urine or feces, which provides information about the stress hormones over a short period of time (minutes to days). In mammals, the use of the hormone cortisol hair can be assessed tension for long periods of weeks and months analysis provides information on chronic stress levels without compromising the associated handling. Here, validation wild rodents hair using peel Foreign adrenal hormone (challenge ACTH) and the application of this technique to assess the stress in East squirrels natural sites connected inhibition of Hair Vitality analysis. Squirrels exposure to the study of recovery and injection per week mark with ACTH (Synacthen warehouse) or saline, with hair that is collected at the end of this challenge. After that, hair and stool samples were collected from squirrels occupation recorded and natural sites to assess the feasibility of hair cortisol compared with the metabolism of cortisol stool. After extraction, it was quantified the concentration of cortisol in the hair and fecal extracts by enzyme immune. Injection of cortisol concentration was significantly elevated in hair samples squirrels ACTH compared to control animals injected (five times) salt. May squirrels living sites registered increased metabolic fecal cortisol levels compared with natural sites, but no difference in the concentration of cortisol hair.Post Your Ad Here
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