Hope for Azoospermia Treatment in India

by Deep Ray Health

Azoospermia is one of the main reasons that couple faces infertility related problems or not able to conceive. Infertility is the most common issue faced by every couple nowadays due to fast-paced lifestyle. For years and years whenever a couple can’t have child it was always woman who was blamed but the truth is many of us didn’t know that every second case out of six is due to male infertility. Azoospermia is a male fertility issue many men face.
The first question arises in our mind is that what is Azoospermia? Azoospermia is the absence of any sperm in the ejaculate. It is the condition of a male not having any measurable level of sperm in his semen due to which a fertile woman is not able to conceive. It is very common reason nowadays for male infertility. Male infertility i.e. difficulty in getting wife pregnancy due to defect in semen as decreased sperm count & low (Poor) motility or abnormal sperms occurs due to above causes. Treatment of low sperm count & motility are discussed below.

Low sperm count or Low (Poor) motility
Nil sperms (Azoospermia)

You should know that testis has two separate functions

Production of normal sperms in semen which needed for pregnancy & normal fertility. The other function of testis is production of male hormones i.e. testosterone & others. So in most patients with nil sperms though semen has absent sperms still production of male hormones remains normal.

How sperms develop ?

When boy becomes of 14 years of age then L.H. & F.S.H. hormone secretion from pituitary increases. The rise in these hormones leads to proliferation of sperm forming cells (Germ Cells) in the testis. These germ cells start multiplying under the effect of above-mentioned pituitary hormones along with assistance of other hormones as testosterones, Growth hormones, Androstenidione, insulin like growth factor-I, Thyroids hormone, paracrine hormone & growth factors. Under the control of above-mentioned hormones germs cells divide & transformed into primary spermatocytes.

Then further maturation of primary spermatocytes to spermatids & then finally into mature spermatozoa (i.e. normal sperms) occurs under the control of above-mentioned hormones. After few weeks of progressive maturation inside the testis these sperms become normally motile & develop the capacity to fertilize the ovum. This total sperm cycle, from first stage to final stage of normal mature sperms is of three months. Thus to produce normal sperms testis should have normal sperm producing germ cells & normal regulating hormones. Any major hindrance in the development of these spermatozoa will lead to absent sperm production resulting into nil sperm..

Diagnosis of Cause of Nil Sperm Count

For correct diagnosis of cause of nil sperm count, we need detail history & physical examinations then certain relevant investigations are required.

History & Physical Examinations : - First step in proper treatment is accurate diagnosis of cause of nil sperm count. So we first try to find out cause. We take detailed history, thorough drug history, and general physical examination, examination of testis, epididymis & testicular veins & sperm carrying duct examinations. These examinations give idea about whether testis is normally developed or not & how is its function. After that depending on likelihood of particular, cause relevant tests are done. All testing facilities are available at our centre. Thus you may consult us at our centre & at same time you may get all tests done. The time taken in getting all the reports ready is 36 hours. So if you are from out of Delhi, you may come here for two days.

Investigation & Diagnosis: - For completes diagnosis of causes of azoospermia (nil sperms) one or more of the following tests may be required as : -

Complete male hormone profile: This profile includes all the male hormone tests which affect testicular development, growth & other genital organ development as well as genital functions. L.H., F.S.H., Testosterone, prolactins, thyroids test,
Antisperm antibody
USG or Doppler study of scrotum & testis
Semen culture sensitivity
Semen fructose
Fine Needle Testicular Biopsy of the testis to look for evidence of spermatogenesis & testicular structure.
Human Sperm-Zona Pellucida Binding Ratio
Human Sperm-Zona Pellucida Pentration test
Genetic Studies
FNAC Testis
Egg penetration test
Molecular genetic studies done in some special cases
Chromosome analysis i.e. Karyotype (chromosome analysis)
Assessment of androgen receptor
Combined Pituitary hormone tests is performed when needed
Immunobead test
MRI head, Hemogram, test for systemic diseases.
Olfactory test is done to find out kallman's syndrome

When it comes to infertility treatment in India, IVF Treatment and ICSI are fast emerging as preferred medical solutions for couples who had almost lost hope of becoming parents. India has become the most preferred place in India for IVF due to team of expertise, latest technology and best infertility clinics in India. Success rate of azoospermia treatments and IVF treatments are much higher than other countries. So becoming a parent for intended couple is no longer a dream.

For more information :

http://www.indiasurgerytour.com/ivf-india/ivf-treatment/india-azoospermia-treatment.html

http://www.indiasurgerytour.com/ivf-india/infertility-surgery/India-infertility-surgery.html