Does The NIPT Test Detect Neural Tube Defects?

by Concepto Diagnostics Choose from our Coronavirus tests

May be an image of text that says "NIPT-Test NIPT NIPT Test NIPT → NIPT Test Detect Neural Tube Defects" In the field of prenatal screening, non-invasive prenatal testing, or NIPT, has become a ground-breaking technology that gives pregnant parents important knowledge about the health of their unborn child. While chromosomal disorders like Down syndrome are well-known to be accurately detected by the NIPT Test in the UK, many prospective parents are curious about whether this cutting-edge screening technique may also detect neural tube defects (NTDs).

May be an image of text that says "NIPT NIPT Test Test"

NIPT and complementary testing

While NIPT is not a reliable way to identify neural tube abnormalities, it can be used in conjunction with other screening techniques. A more thorough evaluation of a baby's general health can be provided by healthcare professionals by integrating NIPT with ultrasonography and other diagnostic instruments. In cases where a high risk of chromosomal abnormalities is shown by the NIPT prenatal screening test in the UK, medical professionals could suggest further testing to confirm or rule out certain disorders, such as neural tube defects.

However, the main question is whether the NIPT test can detect neural tube defects or not.

The answer is no. Neural tube abnormalities are not usually detected by non-invasive prenatal testing (NIPT). By examining cell-free DNA from the fetus in the mother's blood, NIPT is primarily intended to test for common chromosomal abnormalities, such as Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), and Patau syndrome (Trisomy 13).

Spina bifida and anencephaly are two disorders that can arise from anomalies in the formation of the embryonic neural tube, known as neural tube defects. NIPT typically fails to identify these flaws. Instead of using NIPT, neural tube defect screening is frequently carried out using alternative techniques like ultrasonography or certain blood tests.

In cases where neural tube anomalies or other structural problems are suspected, medical professionals could suggest further testing, which could include invasive procedures like amniocentesis or extensive ultrasound tests. Pregnant women should talk to their healthcare professionals about testing choices and any specific concerns they may have to decide the best course of action for their unique situation.

Are there any drawbacks to NIPT testing?

Although a highly effective method for identifying chromosomal abnormalities, NIPT has many drawbacks. Instead of concentrating on structural irregularities or deformities, it analyzes chromosomal material. The latter group includes neural tube defects, which are physical abnormalities as opposed to genetic variations.

The use of ultrasound in prenatal care at the best private healthcare provider in the UK is still essential because it enables medical professionals to see the growing fetus and spot any anatomical problems. Ultrasound exams frequently reveal neural tube anomalies, which provide important details on the baby's spine, skull, and central nervous system.

Conclusion

To sum up, we can say that, although non-invasive prenatal testing (NIPT) represents a significant breakthrough in prenatal screening, prospective parents must be aware of its limitations. Neural tube problems cannot be immediately detected by NIPT or any prenatal screening test in the UK; nonetheless, it is an excellent tool for identifying chromosomal abnormalities. The major method for identifying structural abnormalities in a developing baby is still ultrasound. To make sure they have the most accurate and thorough information regarding their baby's health, expectant parents should have candid conversations with their healthcare professionals at Concepto Diagnostics.

Also Read: What are the basics of Aesthetic Procedures- You Must be Aware Of!