My Personal Opinion: Can You Lose 10 Pounds in 2 Weeks?

Over the years, I’ve been asked the same question by thousands of patients:
“Can I really lose 10 pounds in 2 weeks?”
And here is my honest, personal opinion — yes, it’s absolutely possible for many people, but only when the body is finally placed in the right metabolic environment.

I see patients come in exhausted, frustrated, and confused. They eat “pretty healthy,” they try their best, and yet the scale refuses to move. I don’t believe this is a failure of discipline. I believe this is biology. When your metabolism is sluggish, your appetite signals are disrupted, and your insulin response is unstable, losing weight becomes nearly impossible without medical help.

This is why I started focusing more deeply on non-surgical medical weight loss. As a physician, I’ve witnessed how powerful medications like Tirzepatide can be. The tirzepatide weight loss results I see in my clinic every single week are some of the most impressive outcomes I’ve experienced in my career — and yes, many patients do lose 10 pounds in 2 weeks, especially in their first phase of treatment.

People often ask me how to get Mounjaro, and the truth is, it should always begin with a proper medical evaluation. These medications are extremely effective, but they are also powerful tools that require responsible dosing, monitoring, and guidance. At EndoSlim NY and EndoSlim Florida, we evaluate each patient individually so that the treatment is safe, supervised, and tailored.

From my personal point of view, rapid weight loss is absolutely achievable when several elements work together:

First, nutrition matters — but not in a punishing way. Eating fewer calories, focusing on high-fiber foods, vegetables, fruits, lean proteins, and whole grains creates a gentle caloric deficit that supports fat burning without making you miserable. Patients often tell me they feel fuller and more satisfied within days of starting treatment.

Second, movement matters. I’ve seen patients get incredible results with short bursts of high-intensity workouts (HIIT). Even 10 or 20 minutes can wake up the metabolism. But what truly accelerates progress is medical treatment that corrects hunger hormones and stabilizes insulin response.

That’s why I use treatments such as:
• Tirzepatide (Mounjaro®, Zepbound™)
• Semaglutide (Ozempic®, Wegovy®)
• ESG (Endoscopic Sleeve Gastroplasty) for those needing more powerful help
• Gastric balloon procedures
• Metabolic and nutritional optimization programs

I consider these therapies the most effective tools available for non-surgical weight loss today.

When patients ask me how much they can expect to lose, I always give realistic expectations. But in my personal opinion — supported by years of clinical experience — once we stabilize appetite, reduce cravings, and fix the metabolic pathways, the body finally begins doing what it was supposed to do all along: lose weight efficiently.

And that’s when patients finally say,
“I can’t believe it — I lost 10 pounds in 2 weeks.”

Not because they starved themselves.
Not because they exercised for hours.
But because their metabolism finally started working with them instead of against them.

Watching that transformation — physically and emotionally — is one of the most rewarding parts of my work.