Bladder tumours are abnormal growths that develop in the
tissues of the bladder. They can be either benign (non-cancerous) or malignant
(cancerous), and understanding the differences between them is essential for
early diagnosis, treatment planning, and long-term management. Recognizing the bladdertumour types helps both healthcare professionals and patients make more
informed decisions regarding treatment and recovery. Although bladder tumours
can vary in appearance, origin, and behavior, they all begin with changes to
the cells in the bladder lining or walls.
Squamous Cell
Carcinoma
This type of bladder cancer is less common in areas with
widespread access to medical care but more frequently seen in parts of the
world where chronic bladder irritation is prevalent. Infections like
schistosomiasis (a parasitic disease) and long-term use of urinary catheters
are often contributing factors.
Characteristics:
·
Accounts
for about 4% of bladder cancers in developed countries.
·
Develops
after long-term inflammation or irritation of the bladder lining.
·
Usually
detected at a more advanced stage due to subtle symptoms.
Squamous cell carcinoma tends to be aggressive, and it
typically invades the bladder muscle by the time it is diagnosed. Treatment
often involves surgery, possibly combined with chemotherapy or radiation
therapy.
Adenocarcinoma
Adenocarcinoma originates from glandular cells, which
are not normally found in the bladder. These tumours form mucus-secreting
glands and account for about 1%–2% of bladder cancers.
Characteristics:
·
It
may be linked to bladder exstrophy (a birth defect) or chronic inflammation.
·
Usually
invasive and found at an advanced stage.
·
Requires
surgical treatment in most cases.
Because adenocarcinomas resemble tumours that occur in
the stomach or colon, accurate diagnosis through biopsy and imaging is critical
to avoid misdiagnosis.
Small Cell
Carcinoma
Small cell carcinoma is a rare but highly aggressive
tumour of the bladder. It is a type of neuroendocrine tumour, meaning it
originates from hormone-producing nerve cells.
Characteristics:
·
Comprises
less than 1% of bladder cancers.
·
Spreads
rapidly and usually requires a combination of chemotherapy and radiation.
·
Closely
related to small cell lung cancer in terms of appearance and treatment
response.
Due to its aggressive nature, this tumour type often
requires immediate and intensive treatment. Outcomes depend heavily on how
early the tumour is caught.
Sarcomatoid
Carcinoma and Other Rare Types
Sarcomatoid carcinoma is a very rare tumour that
contains both carcinoma (epithelial) and sarcoma (connective tissue) elements.
It is considered highly aggressive and difficult to treat. Other rare types
include lymphomas, melanomas, and paragangliomas of the bladder, though these
are exceedingly uncommon.
Characteristics:
·
Require
advanced diagnostic testing.
·
Often
resistant to standard treatments.
·
May
be part of a more complex or systemic disease.
These tumours are usually managed on a case-by-case
basis, often in specialized cancer centers with access to tailored therapies.
Benign Bladder
Tumours
While most people focus on malignant tumours, it’s
important to note that the bladder can also develop non-cancerous growths.
These include:
·
Papillomas: Often look like small warts; rare
and non-invasive.
·
Leiomyomas: Tumours of the bladder's smooth
muscle; typically do not cause problems unless they grow large.
·
Hemangiomas: Vascular tumours that may bleed.
Though benign, these tumours can cause symptoms similar
to cancer, such as blood in the urine or urinary frequency, and they often
require removal to prevent complications or confusion during diagnosis.
Diagnosis and
Tests Used
Diagnosing bladder tumours typically involves several
steps:
·
Urine
tests: Detect blood or abnormal
cells.
·
Cystoscopy: Allows direct visualization of
the bladder interior using a camera.
·
Biopsy: Confirms the tumour type through
tissue analysis.
·
Imaging
tests: CT scans or MRIs assess
the extent of tumour spread.
Accurate identification of the tumour type guides the
course of treatment, whether that’s surgery, chemotherapy, radiation, or
immunotherapy.
Treatment Varies
Based on Tumour Type
Each type of bladder tumour requires a different
treatment approach:
·
Urothelial
carcinoma
may be treated with transurethral resection, BCG therapy, or surgery.
·
Squamous
cells and adenocarcinomas
often necessitate more invasive surgery.
·
Small
cell carcinoma
usually demands systemic chemotherapy.
·
Benign
tumours
are often removed without further treatment unless they recur.
Personalized care plans are designed by specialists
based on tumour type, grade, and stage, along with the patient’s overall
health.
Monitoring and
Follow-Up Are Essential
Because bladder tumours have a high chance of returning,
regular monitoring is crucial. Patients typically undergo routine cystoscopies
and urine testing after treatment. The frequency of follow-ups depends on the
tumour type, how aggressive it was, and whether it had spread. Early detection
of recurrence greatly improves the chances of controlling the disease and
maintaining quality of life.
Conclusion
Understanding the different bladder tumour types
is key to timely diagnosis, choosing the right treatment, and managing
long-term health outcomes. While some tumours are slow-growing and
non-invasive, others can spread rapidly and require aggressive intervention.
Staying informed, recognizing symptoms early, and following through with
treatment and monitoring are essential steps in dealing with this condition.