Dr Priya Sharma Healthcare Professional
Several infections have been linked to an increased risk of cancer. Some notable examples include:
Human Papillomavirus (HPV): Certain strains of HPV, especially types 16 and 18, are strongly associated with cervical cancer, anal cancer, and some types of head and neck cancers.
Hepatitis B and C viruses (HBV and HCV): Chronic infection with these viruses can lead to liver cancer (hepatocellular carcinoma).
Epstein-Barr Virus (EBV): EBV is associated with several types of cancers, including Burkitt lymphoma, Hodgkin lymphoma, nasopharyngeal carcinoma, and some gastric cancers.
Human T-cell lymphotropic virus type 1 (HTLV-1): HTLV-1 infection is linked to adult T-cell leukemia/lymphoma (ATLL).
Helicobacter pylori: This bacterium is associated with an increased risk of stomach cancer (gastric adenocarcinoma) and gastric mucosa-associated lymphoid tissue (MALT) lymphoma.
These infections can contribute to the development of cancer through various mechanisms, such as chronic inflammation, interference with cell cycle regulation, and the production of oncoproteins that disrupt normal cellular processes.
Epstein-Barr Virus (EBV) is associated with several types of cancers. Some of the notable cancers linked to EBV infection include:
Burkitt Lymphoma: EBV is implicated in a significant proportion of Burkitt lymphoma cases, especially endemic Burkitt lymphoma found in equatorial Africa. Burkitt lymphoma is a type of non-Hodgkin lymphoma characterized by rapidly growing tumors, often involving the jaw and facial bones.
Hodgkin Lymphoma: In some cases of Hodgkin lymphoma, particularly the nodular sclerosis subtype, EBV infection has been detected in the cancerous cells. However, not all cases of Hodgkin lymphoma are associated with EBV.
Nasopharyngeal Carcinoma (NPC): NPC is a type of head and neck cancer that arises from the nasopharynx, the upper part of the throat behind the nose. EBV infection is strongly linked to the development of nasopharyngeal carcinoma, especially in certain geographic regions where the disease is more prevalent, such as parts of Southeast Asia and North Africa.
Gastric Cancer: EBV has been implicated in a subset of gastric (stomach) cancers, particularly the diffuse type of gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue (MALT) lymphoma.
While EBV infection is associated with an increased risk of these cancers, it's important to note that not everyone infected with EBV will develop cancer. The interplay between viral factors, host immune responses, and environmental factors likely contributes to the development of EBV-associated cancers. Get the best treatment for cancer and full body health checkup at the best hospitals in India.
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Feb 15th 2024 22:25