The Wellness Zone

CA- 125 and full body health checkup

by Dr Priya Sharma Healthcare Professional
Dr Priya Sharma Advanced Healthcare Professional
CA-125 is a protein that is found in higher levels in the blood of women with certain types of cancers, particularly ovarian cancer. It stands for Cancer Antigen 125. CA-125 testing is often used as a tumor marker, which means it can help monitor certain cancers and their response to treatment.

Elevated CA-125 levels can also be caused by other conditions such as endometriosis, uterine fibroids, and pelvic inflammatory disease, among others. It is not used as a definitive diagnostic tool for cancer but rather as part of a comprehensive evaluation of a patient's condition.

In addition to CA-125, several other markers can be used to diagnose and monitor cancer in females, depending on the type of cancer being investigated.
Some common tumor markers include:
CA 15-3: This marker is associated with breast cancer. It is often used to monitor the progression of breast cancer and response to treatment.
CA 19-9: CA 19-9 is associated with pancreatic cancer, but it can also be elevated in other gastrointestinal cancers, including stomach and bile duct cancers.
CEA (Carcinoembryonic Antigen): CEA is a marker used for various cancers, including colorectal cancer, but it can also be elevated in other cancers such as lung, breast, pancreatic, and gastric cancers.
AFP (Alpha-Fetoprotein): AFP is primarily associated with liver cancer (hepatocellular carcinoma) and certain types of germ cell tumors, including testicular cancer and ovarian cancer.
CA 27.29: This marker is used primarily for monitoring breast cancer, especially in cases of metastatic disease.
HE4 (Human Epididymis Protein 4): HE4 is a marker associated with ovarian cancer, particularly in combination with CA-125, to improve the accuracy of diagnosis and monitoring.
These tumor markers are used in conjunction with other diagnostic tests and medical evaluations to help detect cancer, monitor treatment response, and assess disease progression.
The inclusion of CA-125 marker testing in a full body checkup depends on various factors including the individual's medical history, risk factors, and the specific protocol of the full body checkup being performed.

In general, CA-125 testing is not typically included in routine full body checkups for the general population. However, for women who are at higher risk for ovarian cancer due to factors such as family history, certain genetic mutations, or personal medical history, CA-125 testing may be recommended as part of a more comprehensive screening regimen.

Ultimately, the decision to include CA-125 testing in a full body checkup should be made in consultation with a healthcare provider who can assess the individual's risk factors and determine the appropriate screening tests based on current guidelines and evidence-based practices. Get the best cancer diagnosis and treatment, along with a full body health checkup done at the best hospitals in India.
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Jan 30th 2024 21:35

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