What Are Peptides And How They Are Different From SARMs

Peptides are biological molecules that occur naturally. They are found in all living organisms and play a vital role in different biological activities. Similar to proteins, peptides are also formed (synthesized) naturally from transcription of a sequence of the genetic code, DNA. Transcription is the biological process, where a specific DNA gene sequence is copied into a messenger molecule, mRNA, which further carries the code for a given peptide or a protein. Reading from the mRNA, a chain of amino acids is joined together by the peptide bonds which later form into a single molecule. There are 20 such naturally-occurring amino acids and, like letters are combined to form words, they can also be combined into immense variety of different molecules.

When a molecule consist 2-50 amino acids, then it is called a peptide, whereas a larger chain consisting more than 50 amino acids is generally referred to as a protein.

If we talk about human body, peptides are found in all cells and tissues, which perform wide range of essential functions. Maintenance of appropriate concentration and activity levels of peptides is important to achieve homeostasis and maintaining health. The function that a peptide carries out is dependent on the various types of amino acids involved in the chain and their sequence, as well as the specific shape of the peptide. Peptides often act as hormones and constitute biologic messengers that carry information from one tissue through the blood to another.

Two common classes of hormones are peptide hormones and steroid hormones. Peptide hormones are produced in glands, and in the number of other tissues like the stomach, the intestine and the brain. For example peptide hormones are those involved in blood glucose regulation, including insulin, glucagon-like-peptide 1 (GLP-1) and glucagon, and those which regulate appetite, including ghrelin.

For a peptide to exert its effect, it needs to be bind to a specific receptor for that peptide, which has to be located in the membrane of relevant cells. A receptor penetrates the cell membrane and consists of an extracellular domain where the peptide binds. It is an intracellular domain through which the peptide exerts its function upon binding and activation of the receptor. An example of such receptor is the GLP-1 receptor, which is located on beta cells in the pancreas. Upon activation of the receptor by natural GLP-1 or a peptide analog the cell is stimulated through a series of biological events to release insulin.

There are many online stores from where peptides can be purchased, however it is not yet confirmed that it is legal or not or has been confirmed by FDA or not. For now these peptides are used for research purposes only. But still you can buy bremelanotide on some hosting websites, while it has not been legalized. Bremelanotide or PT-141 Bremelanotide is the generic term for a research peptide being studied for its possible use that helps in improving sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). It was developed from the tanning peptide Melanotan 2, which is a synthetically produced variant of a peptide hormone, naturally produced in the body that stimulates melanogenesis, also known as alpha-Melanocyte stimulating hormone.

 Despite the fact that there has been plenty of research on PT-141 (Bremelanotide) in relation to how it functions and the benefits that can be derived, it should be emphasized that the peptide is still just intended for scientific study only at this point in time. Likewise, instead of buy bremelanotide you may also buy pt 141 bremelanotide which is the same thing, with only difference is that pt 141 is its investigation code.

Difference Between Peptides And SARMs

SARMs are a type of androgen receptor ligands which selectively bind themselves to the androgen receptors. They build up muscle power and serve as a fast acting performance enhancer. Therefore, SARMs are a good anabolic steroid replacement as they do not show the signs of Liver damage when taken orally. Because of its unique advantage and to earn money, some of the manufactures have made these SARMs into bodybuilding-focused products. But still, due to regulations and other issues, Companies were forced to stop selling SARMs in the US. But in other countries like Europe, people are still able to purchase sarms from the Enhanced Athlete EU website.

Also, SARMs can generate an effect which is similar to the testosterone but, with fewer side effects as shown by testosterone. One of the most important features of SARMs is that different types of SARMs can selectively target various tissues. That means, some SARMs are specific for muscle building while others are specific for leaning out fat in the body. Some examples of SARMs include RAD 140, LGD 4033, Ostarine, Andarine (S-4, GTx-007), BMS-564,929, etc. However the SARMs industry is not yet regulated so one has to really get ensured 100% before one go and buy liquid sarms as these are not for human consumption.

While on the other side Peptides are a type of bodybuilding supplements which comprises of polypeptide chains with less than 50 amino acids. The amino acid chains with 10 to 100 amino acids are known as polypeptides while polypeptides with more than 50 amino acids are known as proteins. However, peptides are better than proteins and creatine which is used in muscle building.

Moreover, peptides produce less-long side effects in comparison to the other steroids used for this purpose. They are used as GH secretagogue and are responsible for increasing the secretion of growth hormone. Also, there are two main forms of peptides: synthetic forms of GHRH (growth hormone releasing hormone) and GHRP (growth hormone releasing peptides). 

Another difference between SARMs and peptides is that SARMs are synthetic while peptides can be either synthetic or natural. SARMs bind to the androgen receptors in the muscle and bones, increasing their growth, while peptides increases the release of growth hormone. SARMs produce a highly selective effect on bone and muscle building while the selective effect of peptides on muscle building is comparatively low. Therefore, both SARMs and peptides can be used to increase bone and muscle mass. However, the main difference between SARMs and peptides lies is their method of action and selectivity.

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Created on Sep 19th 2019 04:48. Viewed 401 times.

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