Articles

Importance of Trigger Shot in IVF

by Shivani Sachdev Director at SCI IVF Hospital
The trigger shot is an important part of ovulation induction in the IVF process that helps to proceed eggs to the maturation division or meiosis before retrieving eggs. Meiosis is an egg division phase, where chromosomes become 46 to 23. After meiosis, eggs are retrieved and fertilized in the lab. For a successful IVF treatment, contact SCI IVF Hospital – the best IVF clinic in Delhi NCR.

Who Need Trigger Shot?
The trigger shot is given in combination with other medication in the following cases.
•    If the female body is unable to release eggs or suffers from anovulation.
•    If a female has weak ovulation.
•    If a woman is at risk of ovarian hyperstimulation syndrome.
•    If controlled ovulation is required in the IVF process.

How Trigger Shots are Helpful in IVF?
Human chorionic gonadotropin (hCG) and LH (luteinizing hormone) are pregnancy hormones. hCG triggers the follicles to break and release an egg. LH is secreted from the pituitary gland right before ovulation and is responsible for the maturation of eggs. If a woman cannot ovulate, trigger shots are used in IVF. Dr. Shivani Sachdev Gour – the best IVF doctor in Delhi elucidates the following advantages of trigger shots.
  • Ovaries Stimulation: In ovarian stimulation, FSH and LH gonadotropic hormones injections are given to push the ovaries for egg growth. Some of the medications used in Ovarian Stimulation are Noravel, Pregnyl, and Lupron.
  • For Meiosis: Trigger shot helps eggs to reach the meiosis phase. It reduces the number of chromosomes from 46 to 23 by eliminating half of the chromosomes from the egg’s nucleus. The eliminated chromosomes accumulate in a membrane outside the nucleus and are ejected later.
  • Ensures Euploid Embryo: Euploid embryo has 46 chromosomes, where 23 are gained from the egg and 23 from the sperm. Trigger shot ensures exactly 23 chromosomes must stay in the egg nucleus before going into the fertilization process. Pregnancy cannot achieve by an unequal number of chromosomes in an embryo.


When to Take Trigger Shot during IVF Process?
The patient is monitored by the doctor, who instructs the correct time to take the trigger shot. Your doctor tracks your complete menstrual cycle and suggests taking the shot when an appropriate quantity and size of follicles have developed. Follicles of diameter 15 mm to 22 mm are considered correct for conception and are achieved after 8 to 12 days of your menstrual cycle. Pregnancy chances decrease if eggs are either under matured or over matured. You can take trigger shots by yourself in the form of injections. Trigger shots need to be taken 36 hours prior to egg retrieval. Even a delay of few hours can affect the timing of the complete treatment cycle. In the IVF process, after 36 hours of the trigger shot, eggs are retrieved and fertilized by sperms in the lab. Fertilized eggs are then transferred to the mother’s womb for further development.

Are there any Side-effects of Trigger Shot?
The majority of patients do not feel any uneasiness; however, some possible side effects are listed below.

•    Stomach discomfort or pelvic pain.
•    Irritation or tenderness at the area of injection.
•    Swelling in ovaries.
•    Vomiting, diarrhea, or nausea.
•    Blood clot or discomfort in urine passing.


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About Shivani Sachdev Innovator   Director at SCI IVF Hospital

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Joined APSense since, August 17th, 2021, From New Delhi, India.

Created on Sep 6th 2021 13:36. Viewed 264 times.

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