Gene Expression Reagents Market will Continue to Grow Strongly Through 2019
Gene expression is a
process that results in the synthesis of a functional gene product with the
help of the information coded on genes. These products usually are proteins
with respect to coding genes but in case of non-coding genes such as tRNA
(transfer RNA), or RNA (ribosomal RNA), the functional product is a functional
RNA. The process of gene expression is significant in both prokaryotes
(bacteria) and eukaryotes (multicellular organisms) in order to ensure the
generation of macromoleular machinery for their life. Gene expression comprises
transcription and translation processes. Transcription (DNA to RNA) refers to
production of RNA copies of DNA with the help of the enzyme RNA polymerase.
While translation (RNA to protein) is a process that results in the synthesis
of proteins based on the information on the coding genes (messenger RNA). There
is a possibility of the alteration of several steps in gene expression process
such as in RNA splicing, post-translational modification of proteins and
others. Gene regulation is the basis for morphogenesis, cellular
differentiation and versatility and renders cell control over structure and
function of the genes.
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Gene expression profiling
refers to the process of measuring the activity (expression) of several genes
at once in to understand the cellular functions. This analysis can facilitate
scientists to identify the molecular basis of phenotypic differences and also
enables selection of gene expression targets for the future research studies.
The various analysis techniques employed for gene expression are SAGE (serial
analysis of gene expression), Real Time PCR-based gene expression profiling,
microarray analysis, transcriptome sequencing and others. Gene expression
reagents are the chemicals used in gene expression studies performed to
determine the gene expression patterns. Sample preparation and isolation kits,
sample labeling and amplification kits, TaqMan Gene Expression assay kits, gene
expression hybridization kits and others are some of the examples of the
commercially available gene expression reagents kits. Confirmation of
appropriate gene expression is essential in order to ensure normal functioning
of genes and any deviation from the normal expression pattern might result in
the development of some disorder either genetic or acquired. Also, regulation
of faulty gene expression inhibits the production of faulty functional
products. For example, in case of cancer patients, RNA silencing is employed
that includes the silencing of the cancerous gene expression.
The market for gene
expression reagents can be analyzed on the basis of the reagents used in gene
expression profiling along with application areas and geography. The reagents
can be further segmented into the reagents used in PCR, Microarray, SAGE and
others. The application areas that can be covered are drug discovery and
research, biomarkers identification, clinical diagnostics and others.
Geographically the market can be analyzed on the basis of four major regions
namely North America, Asia-Pacific, Europe and RoW.
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The major
factors favoring the growth of the market are consistent technological
advances, increased intensity of research and development activities and
development of gene expression databases across the globe. In addition,
increased investments and funding by the government for genetic research along
with elevated awareness levels further propel the market growth. On the other
hand, high instrumentation costs along with lack of technical expertise in this
field would impede the growth of the market. Owing to several advantages and
increasing preference for personalized medicine, the scope for growth and
uptake of gene expression studies will also increase and in turn increase
uptake of gene expression reagents. Affymetrix, Inc., Illumina, Inc., Qiagen N.V.,
Thermo Fisher Scientific (Life Technologies Corporation), Bio-Rad Laboratories,
Inc. and Agilent Technologies are some of the companies competing in gene
expression reagents market.
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North
America
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Asia
Pacific
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Europe
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Rest
of the World
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Market
growth drivers
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Factors
limiting market growth
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Current
market trends
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Market
structure
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Market
projections for upcoming years
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