In the
recent years, bioethanol has emerged as important source of energy due to
exhaustion of existing energy supplies around the world. Moreover, the growing
environmental awareness among the consumers has led to the shift towards the
use of the enzymes in bioethanol production and mitigate the use of chemical
catalysts. Enzymes are used in various
other industrial applications such as food & beverage processing,
detergents, textiles & leather, paper & pulp, wastewater treatment, feed,
starch processing, cosmetics & personal care products, and oilfield &
fine chemicals. The major types of enzymes used in the industrial and specialty
applications are carbohydrases (amylases, cellulases, other carbohydrases such
as pectinase, lactase, mannanase, and pullulanase), proteases, lipases, and
other types such as isomerases, transferases, betaglucanases, arabinoxylanases,
amyloglucosidase, and pullulanase. Enzymes are also used in various specialty
applications such as pharmaceuticals, research & biotechnology,
diagnostics, and biocatalysts. Enzymes
market is projected to reach USD 16.9 billion by 2027 growing at a CAGR
of 6.8% from 2022 to 2027.
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The enzymes
market is anticipated to witness potential opportunities in the future by its specialty
applications in different industries like pharmaceuticals. The
pharmaceutical industry dominated the specialty enzyme by application segment
in 2022 with USD 2.4 Billion and is expected to grow USD 3.2 Billion by 2027. The players in the market are involving in
expansion of production facilities and agreement to increase their penetration
in the market. For instance, in June 2022, Merck KGaA has expanded its
production facility of Pharma ingredients like High Potent Active
Pharmaceutical Ingredients (HPAPI) production capacity in Wisconsin, US. In September 2021, Codexis has extended the
agreement with Merck to supply a proprietary enzyme used in the manufacturing
process for sitagliptin, the active pharmaceutical ingredient
Based on product
type, the market for enzymes is segmented as industrial enzymes and specialty
enzymes. The industrial enzymes product type dominated the enzymes market in
2021. With advancements in technology, the application of enzymes expanded in
various industrial applications. The ability of industrial enzymes to catalyze
the chemical reactions and the increase in the number of applications have led
to the growth of the enzymes market. Specialty enzyme’s demand in the research
& biotechnology end-market would benefit from the reduction in DNA
sequencing costs and the increase of new sequencing techniques.
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The growth
potential for enzymes market has been projected to be high due to the
increasing product launches, collaborations, partnerships, and acquisitions by
the players in the industry. For instance, in 2022, Kerry group has acquired
c-LEcta which specializes in precision fermentation, biotransformation and
optimized bioprocessing in order to create high-value enzymes and ingredients.
The objective of this acquisition is to expand its expertise, technology
portfolio and manufacturing capabilities of enzymes. In December 2021, Codexis
has launched a product named “Codex HiTemp Reverse Transcriptase”. This enzyme
is specifically engineered and optimized for enhanced thermostability and
robustness to address known challenges in handling clinical samples. In
February 2021, Merck KGaA partnered with BioNTech to supply urgently needed
lipids and to increase the amount of lipid delivery. In 2020, Merck KGaA
collaborated with Mammoth Biosciences (US) to scale-up and commercial
production of SARS CoV-2 test.