Risk and common side effects associated with non-steroidal anti-inflammatory drugs

by Camili Smith Medical Consultant Non-steroidal anti-inflammatory medications also known as NSAIDs are used to reduce inflammation and pain. These medications are easily available over-the-counter and are some of the widely used medications in the world. Many people take this medication without knowing the side effects and risk associated with them. These medications are used to reduce inflammation and relieve pain, and are often used to treat a variety of conditions such as backaches, sprains, migraines, dental pain, menstrual cramps, bursitis, and muscle aches.

Everyday millions of people take non-steroidal anti-inflammatory medication in order to reduce pain and swelling. As these medications are available over the counter, people tend to take it even if they experience slightest ache.

Risk associated with NSAID:

Long term risk associated with NSAID:
• Gastrointestinal problems and upper GI tract injuries are some serious side effect of NSAIDs. The enzyme inhibited by NSAIDs reduces the production of prostaglandins that protect the lining of the stomach. If the protective mucus layer of the stomach is not present, then acids can cause small erosions in the stomach and duodenum, which can burst and lead to bleeding also.
• Short-term effects of NSAIDs embrace an upset stomach (dyspepsia), indigestion, nausea, pain, and diarrhea. Prolonged use of NSAIDs can develop peptic ulcers and gastrointestinal perforations (holes in the wall of the stomach or intestines). The danger increases for elderly people or for those who have a history of ulcers. People who experience chronic pain and prolonged intake of NSAID; suffer more from ulceration and other related problems than people who take an occasional pill.

Cardiovascular risk increases:
While COX-2 inhibitors may pose lesser gastrointestinal problems, they have a serious downside. It has also been discovered that these drugs increase the risk of heart attacks and other cardiovascular problems. Except aspirin, all other NSAIDs need to have a black box warning that states that NSAIDs may increase the risk of serious cardiovascular clotting events, strokes and myocardial infarction. The risk is higher for people who have high blood pressure, cardiovascular disease, or those who take the medications for prolonged duration.

Common side effects frequently embrace:
• Headaches
• Dizziness
• Skin rashes
• Drowsiness
• Edema (Retention of fluid)

Avoid NSAID:
There are certain medical conditions and situations where NSAID can be evaded as it increases the severity of the condition. Avoid NSAIDs when:
• Rhinitis (Leads to inflammation of mucous membrane of the nose)
• Aspirin-induced asthma
• Chronic urticaria
• Pregnancy

Camili Smith is a Medical Student and a freelancer who is specialized in writing. He is associated with many Pharmacies for whom he writes articles based on health issues and generic drugs like Zithromax, Generic Xenical, Nexium, Generic Zyvox.

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Created on Dec 31st 1969 18:00. Viewed 0 times.

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