Advancement In Biotechnology- Know About Generation Sequencing

by Lara Ponting Consultant Next-generation sequencing, which is also known as high-throughput sequencing. These terms are used to describe a number of different modern sequencing technologies, this include:

* Roche 454 sequencing
* Illumine (Solexa) sequencing
* Ion torrent: Proton / PGM sequencing
* Solid sequencing

These latest technologies allow the professionals to synchronize RNF and DNA much more quickly and cheaply than the previously used technology. This has changed the study of molecular biology and genomics.

The high demand for low-cost sequencing has driven the development of high-throughput sequencing, which is also termed as next generation sequencing (NGS). Thousands and millions of sequences concurrently produced in next-generation sequencing process. This process has become a commodity. With the commercialization of various affordable desktop sequencers. The best next generation sequencing will reach by more traditional wet-lab scientists. Lately, genome-wide scale procedure analysis is increasingly being used as a keystone to foster the discovery in biomedical research.

DNA sequencing is done by the scientists in a very fine manner. In the first step the DNA must be extracted from the chromosome that keeps it, and then it is broken up into smaller strands. Each small form is used to make a set of parts, each one's base is shorter than the one before it. Later, the parts are separated by a gel and then a fluorescent dye is used to identify each individual type of nucleotide. Then a computer program generates the sequences of the nucleotides into the units of about 500 bases that just replicate the strand that the DNA was taken from. These units are then bent to make a very long strand of DNA sequencing. The resulting DNA sequencing is then shared with other scientists in computer databases.

Next generation sequencing technologies includes numerous methods, which are sorted broadly as sequencing and imaging, template preparation, and data analysis. The unique combination of specific rules differentiates one technology from another. This also determines the type of data that is produced from each platform. However, the basic sample process requirements, so called library construction, are shared among all of the technology platforms. You can find some best companies, who offers MNICRORNA and MRNA sample library construction kits, which allows fast and cost-effective NGS sequencing. The following are the advantages to can avail:

 (1) Efficient work-flow process
 (2) Inexpensive chemical agent
 (3) Easy to use and all-in-one kit.

Such features enhances the productivity by shortening the time required for library preparation and decreases the potential human error rate. You can find best frozen tissue sections and other related products online.

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Created on Dec 31st 1969 18:00. Viewed 0 times.

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